Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 2/20 | 0.39 |
| ▸ | ELANE | P08246 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | GPR3 | P46089 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 2/20 | 0.31 |
| ▸ | PLAU | P00749 | 2/20 | 0.31 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 2/20 | 0.30 |
| ▸ | HTT | P42858 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27344743 | 0.77 | ALDH1A1 (0.47) | MPOSMN1; SMN2GPR3ALDH1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL27804686 | 0.75 | ALDH1A1 (0.45) | MPOSMN1; SMN2GPR3ALDH1A1CYP1A2 | |
| SCHEMBL29162356 | 0.74 | GLS (0.47) | ELANESMN1; SMN2GPR3F2PLAU | |
| SCHEMBL20674507 | 0.73 | ELANE (0.38) | MPOELANEGPR3F2PLAU | |
| SCHEMBL15488683 | 0.70 | MPO (0.37) | MPOELANESMN1; SMN2GPR3F2 | |
| Oxalic Acid SCHEMBL28043151 | 0.69 | ELANE (0.40) | ELANESMN1; SMN2F2PLAUALDH1A1 | |
| SCHEMBL1969701 | 0.68 | ELANE (0.49) | ELANESMN1; SMN2F2PLAUALDH1A1 | |
| SCHEMBL627443 | 0.65 | SMN1; SMN2 (0.40) | SMN1; SMN2ALDH1A1CYP1A2CYP2C19KDM4E | |
| SCHEMBL1408375 | 0.60 | SMN1; SMN2 (0.56) | SMN1; SMN2GPR3ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL14072748 | 0.58 | GPR3 (0.50) | GPR3ALDH1A1CYP2C19KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3399968-B1 | SELECTIVE INHIBITORS OF CLINICALLY IMPORTANT MUTANTS OF THE EGFR TYROSINE KINASE | CS PHARMATECH LTD (KY) | 2021-10-20 | — | — | EP | disclosed |