SCHEMBL23937960

SCHEMBL23937960

O=C1C=Cc2ccc(C3CC3)n21

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FAAH O00519 1/20 0.30
MGLL Q99685 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29190318 0.62 MGLL (0.38) FAAHMGLL
SCHEMBL212347 0.56 ALDH1A1 (0.43) MGLL
SCHEMBL18209593 0.56 ALDH1A1 (0.48)
SCHEMBL11088343 0.56 MAOA (0.41)
SCHEMBL9719942 0.56 TLR9 (0.59) FAAHMGLL
SCHEMBL24079397 0.55 ALDH1A1 (0.52)
SCHEMBL1059882 0.55 ALDH1A1 (0.52)
SCHEMBL25118469 0.55 ALDH1A1 (0.52)
SCHEMBL15492440 0.55 ALDH1A1 (0.52)
SCHEMBL25434872 0.55 ALDH1A1 (0.52)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3399968-B1 SELECTIVE INHIBITORS OF CLINICALLY IMPORTANT MUTANTS OF THE EGFR TYROSINE KINASE CS PHARMATECH LTD (KY) 2021-10-20 EP disclosed