Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 18/20 | 0.38 |
| ▸ | FAAH | O00519 | 6/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | ATM | Q13315 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | GSK3A | P49840 | 2/20 | 0.31 |
| ▸ | GSK3B | P49841 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | XBP1 | P17861 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.31 |
| ▸ | CBFB | Q13951 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL426650 | 0.63 | — | — | |
| SCHEMBL23937960 | 0.62 | FAAH (0.30) | MGLLFAAH | |
| SCHEMBL6991905 | 0.61 | NOTUM (0.46) | MGLLFAAHTLR9HSP90AA1ALDH1A1 | |
| SCHEMBL1838889 | 0.55 | MGLL (1.00) | MGLLFAAHHSP90AA1ALDH1A1HTT | |
| SCHEMBL94730 | 0.55 | MGLL (1.00) | MGLLFAAHHSP90AA1ALDH1A1HTT | |
| SCHEMBL13575342 | 0.55 | GSK3B (0.45) | MGLLALDH1A1HTTATMGSK3A | |
| SCHEMBL3697751 | 0.55 | — | — | |
| SCHEMBL349418 | 0.54 | MGLL (0.50) | MGLLFAAHTLR9HSP90AA1ALDH1A1 | |
| SCHEMBL375596 | 0.54 | ADORA3 (0.47) | HSP90AA1ALDH1A1HPGD | |
| SCHEMBL3778737 | 0.54 | MGLL (0.61) | MGLLFAAHTLR9HSP90AA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117567463-A | Synthesis method of indolizine-3, 5-dione | 菏泽学院 | 2024-02-20 | — | — | CN | disclosed |
| CN-117567463-A | Synthesis method of indolizine-3, 5-dione | 菏泽学院 | 2024-02-20 | — | — | CN | disclosed |
| CN-117567463-A | Synthesis method of indolizine-3, 5-dione | 菏泽学院 | 2024-02-20 | — | — | CN | disclosed |