Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.47 |
| ▸ | CETP | P11597 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CCR5 | P51681 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CTRC | Q99895 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CCR6 | P51684 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23944616 | 0.86 | MBOAT4 (0.47) | MBOAT4CETPALDH1A1CYP3A4TSHR | |
| SCHEMBL23944994 | 0.81 | MBOAT4 (0.47) | MBOAT4CETPALDH1A1CYP3A4TSHR | |
| SCHEMBL29414961 | 0.77 | CETP (0.51) | MBOAT4CETPALDH1A1CYP3A4TSHR | |
| Ammonia Solution, Strong SCHEMBL27836903 | 0.76 | CETP (0.50) | MBOAT4CETPALDH1A1CYP3A4TSHR | |
| Ammonia Solution, Strong SCHEMBL27817446 | 0.76 | CETP (0.50) | MBOAT4CETPALDH1A1CYP3A4TSHR | |
| SCHEMBL7537786 | 0.75 | CETP (0.52) | MBOAT4CETPALDH1A1CYP3A4TSHR | |
| SCHEMBL7541915 | 0.75 | CETP (0.52) | MBOAT4CETPALDH1A1CYP3A4TSHR | |
| SCHEMBL23944942 | 0.74 | MBOAT4 (0.56) | MBOAT4CETPALDH1A1CYP3A4TSHR | |
| SCHEMBL28774981 | 0.74 | MBOAT4 (0.48) | MBOAT4CETPALDH1A1CYP3A4TSHR | |
| SCHEMBL22780788 | 0.74 | ALDH1A1 (0.50) | ALDH1A1CYP3A4TSHRMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210323913-A1 | SIGMA RECEPTOR BINDERS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2021-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210323913-A1 | SIGMA RECEPTOR BINDERS | SIGMAR1, OPRK1, OPRL1 | MBOAT4 3761/4885CETP 1264/4885ALDH1A1 431/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.