SCHEMBL23946307

SCHEMBL23946307

CCc1nc(-c2ccc(-c3ccccc3)cc2)c2c(-c3ccccc3)cccc2n1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 3/20 0.40
PDE4B Q07343 3/20 0.40
PDE4C Q08493 3/20 0.40
PDE4D Q08499 3/20 0.40
PDE3B Q13370 3/20 0.40
PDE3A Q14432 3/20 0.40
TDP1 Q9NUW8 2/20 0.39
DHODH Q02127 1/20 0.39
KCNH2 Q12809 2/20 0.38
KDM4E B2RXH2 4/20 0.37
LMNA P02545 4/20 0.37
ALDH1A1 P00352 4/20 0.37
GAA P10253 2/20 0.37
L3MBTL1 Q9Y468 3/20 0.36
NPSR1 Q6W5P4 2/20 0.36
GPR84 Q9NQS5 1/20 0.36
JAK2 O60674 1/20 0.36
IGF1R P08069 1/20 0.36
PIM1 P11309 1/20 0.36
SRC P12931 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20483821 0.81 ADORA1 (0.45) PDE4APDE4BPDE4CPDE4DPDE3B
SCHEMBL23946292 0.80 KCNH2 (0.49) TDP1DHODHKCNH2KDM4ELMNA
SCHEMBL20035085 0.80 ADORA2A (0.51) TDP1DHODHKDM4ELMNAALDH1A1
SCHEMBL23946294 0.77 CRHR1 (0.45) PDE4APDE4BPDE4CPDE4DPDE3B
SCHEMBL23946310 0.76 KCNH2 (0.51) TDP1DHODHKCNH2KDM4ELMNA
SCHEMBL6329097 0.76 NUDT1 (0.55) KDM4ELMNAALDH1A1GAAL3MBTL1
SCHEMBL5988414 0.74 MEN1 (0.50) KCNH2LMNAL3MBTL1JAK2KCNA5
SCHEMBL23946343 0.72 KCNH2 (0.44) TDP1DHODHKCNH2KDM4ELMNA
SCHEMBL27319264 0.71 ALOX5 (0.45) PDE4APDE4BPDE4CPDE4DPDE3B
SCHEMBL23946340 0.71 KCNH2 (0.46) TDP1DHODHKCNH2KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210328153-A1 ELECTROLUMINESCENT MATERIALS AND DEVICES Beijing Summer Sprout Technology Co., Ltd. (CN) 2021-10-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210328153-A1 ELECTROLUMINESCENT MATERIALS AND DEVICES IDO1, IDO2, AZI2 PDE4A 601/4885PDE4B 380/4885PDE4C 155/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.