SCHEMBL23948519

SCHEMBL23948519

CC(C)CCN1C(=O)CC(C)C1=O

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.41
TSHR P16473 1/20 0.41
ALDH1A1 P00352 3/20 0.39
GAA P10253 1/20 0.39
SORT1 Q99523 2/20 0.39
PIK3CD O00329 1/20 0.37
MEN1 O00255 1/20 0.35
CYP2C19 P33261 1/20 0.35
KMT2A Q03164 1/20 0.35
MME P08473 1/20 0.33
CYP19A1 P11511 1/20 0.33
POLB P06746 1/20 0.33
CCKBR P32239 1/20 0.33
HTT P42858 1/20 0.33
OPRK1 P41145 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21954067 0.89 CYP19A1 (0.36) LMNATSHRALDH1A1GAASORT1
SCHEMBL20845390 0.87 FKBP1A (0.35) LMNATSHRALDH1A1GAAPIK3CD
SCHEMBL14589097 0.84 CYP19A1 (0.39) ALDH1A1GAAPIK3CDMEN1KMT2A
SCHEMBL24594822 0.83 LMNA (0.36) LMNATSHRALDH1A1PIK3CDCYP19A1
SCHEMBL15199705 0.82 ALDH1A1 (0.33) LMNATSHRALDH1A1GAAMME
SCHEMBL12194920 0.81 PIK3CD (0.47) ALDH1A1GAAPIK3CDMMECYP19A1
SCHEMBL24671656 0.81 CYP19A1 (0.34) LMNATSHRALDH1A1GAACYP19A1
SCHEMBL16566171 0.80 CYP19A1 (0.44) LMNAALDH1A1GAAMEN1KMT2A
SCHEMBL12410325 0.80 CYP19A1 (0.41) ALDH1A1GAAMEN1KMT2ACYP19A1
SCHEMBL22646532 0.80 LMNA (0.41) LMNATSHRALDH1A1GAASORT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230265429-A1 SKELETAL MUSCLE DELIVERY PLATFORMS AND METHODS OF USE THEREOF Arrowhead Pharmaceuticals, Inc. 2023-08-24 US disclosed
WO-2021209007-A1 ANTIBODY-DRUG CONJUGATE SHENZHEN ENDURING BIOTECH, LTD. (CN) 2021-10-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230265429-A1 SKELETAL MUSCLE DELIVERY PLATFORMS AND METHODS OF USE THEREOF MUSK, MYLK2, TNNC1 LMNA 1041/4885TSHR 1489/4885ALDH1A1 2528/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.