Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.31 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4623201 | 0.72 | SRD5A1 (0.40) | SRD5A1 | |
| SCHEMBL5682088 | 0.72 | ESR1 (0.49) | CYP3A4MAPT | |
| SCHEMBL6260842 | 0.72 | ESR1 (0.49) | CYP3A4MAPT | |
| SCHEMBL4589641 | 0.64 | LMNA (0.39) | CYP3A4ALDH1A1MAPT | |
| SCHEMBL23568631 | 0.64 | NR3C1 (0.46) | CYP3A4ALDH1A1 | |
| SCHEMBL23569929 | 0.64 | NR3C1 (0.46) | CYP3A4ALDH1A1 | |
| SCHEMBL4589211 | 0.63 | LMNA (0.38) | CYP3A4ALDH1A1MAPT | |
| SCHEMBL4588704 | 0.62 | ESR1 (0.40) | CYP3A4MAPT | |
| SCHEMBL6232522 | 0.59 | NR3C1 (0.41) | CYP3A4ALDH1A1MAPT | |
| SCHEMBL6233082 | 0.59 | NR3C1 (0.41) | CYP3A4ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11787835-B2 | C19 scaffolds and steroids and methods of use and manufacture thereof | TRUSTEES OF DARTMOUTH COLLEGE (US) | 2023-10-17 | — | — | US | disclosed |
| US-20210323998-A1 | C19 SCAFFOLDS AND STEROIDS AND METHODS OF USE AND MANUFACTURE THEREOF | TRUSTEES OF DARTMOUTH COLLEGE | 2021-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210323998-A1 | C19 SCAFFOLDS AND STEROIDS AND METHODS OF USE AND MANUFACTURE THEREOF | CYP17A1, HSD17B7, CYP11A1 | CYP3A4 2472/4885ALDH1A1 4090/4885MAPT 2064/4885 |
| US-11787835-B2 | C19 scaffolds and steroids and methods of use and manufacture thereof | CYP17A1, HSD17B7, CYP11A1 | CYP3A4 2472/4885ALDH1A1 4090/4885MAPT 2064/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.