Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CFTR | P13569 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 3/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
| ▸ | HPGDS | O60760 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25698171 | 0.94 | PDE4B (0.31) | IRAK4ACSS2 | |
| SCHEMBL23958776 | 0.90 | LMNA (0.36) | LMNATP53CFTRALDH1A1SMN1; SMN2 | |
| SCHEMBL23958797 | 0.90 | CFTR (0.36) | LMNATP53CFTRALDH1A1SMN1; SMN2 | |
| SCHEMBL23958859 | 0.86 | CFTR (0.34) | LMNATP53CFTRALDH1A1SMN1; SMN2 | |
| SCHEMBL23958874 | 0.85 | CTSA (0.35) | ROCK2ROCK1ACSS2FFAR1 | |
| SCHEMBL23958810 | 0.84 | CFTR (0.34) | LMNATP53CFTRSMN1; SMN2MAPT | |
| SCHEMBL26766103 | 0.83 | IRAK4 (0.39) | LMNATP53CFTRKCNH2IRAK4 | |
| SCHEMBL30007052 | 0.82 | CFTR (0.34) | CFTRSMN1; SMN2CNR2CNR1ROCK2 | |
| SCHEMBL25687509 | 0.82 | CFTR (0.34) | CFTRSMN1; SMN2CNR2CNR1ROCK2 | |
| SCHEMBL25687494 | 0.82 | CFTR (0.37) | CFTRSMN1; SMN2CNR2ROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021214136-A1 | RSV INHIBITING 3-SUBSTITUTED QUINOLINE AND CINNOLINE DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2021-10-28 | — | — | WO | disclosed |