Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23958810 | 0.94 | CFTR (0.34) | CFTRLMNATP53PDE4BP2RX7 | |
| SCHEMBL23958776 | 0.90 | LMNA (0.36) | CFTRLMNATP53PDE4BP2RX7 | |
| SCHEMBL23958652 | 0.90 | LMNA (0.33) | CFTRLMNATP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL23958859 | 0.86 | CFTR (0.34) | CFTRLMNATP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL25698171 | 0.85 | PDE4B (0.31) | PDE4BACSS2 | |
| SCHEMBL23958874 | 0.85 | CTSA (0.35) | PDE4BACSS2ROCK2ROCK1GABRA5 | |
| SCHEMBL23958656 | 0.84 | SSTR5 (0.34) | EPHX2 | |
| SCHEMBL25698133 | 0.84 | PDE4B (0.35) | PDE4BP2RX7HCRTR1HCRTR2ACSS2 | |
| SCHEMBL26766103 | 0.83 | IRAK4 (0.39) | CFTRLMNATP53 | |
| SCHEMBL25687503 | 0.82 | CFTR (0.38) | CFTRPDE4BHCRTR1HCRTR2ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021214136-A1 | RSV INHIBITING 3-SUBSTITUTED QUINOLINE AND CINNOLINE DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2021-10-28 | — | — | WO | disclosed |