Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 4/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.31 |
| ▸ | CTSA | P10619 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
| ▸ | BRAF | P15056 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23958793 | 0.90 | CFTR (0.35) | GSK3BMAPK14 | |
| SCHEMBL23958709 | 0.88 | FFAR1 (0.31) | MAPK1FFAR1 | |
| SCHEMBL23958856 | 0.77 | PGR (0.30) | — | |
| SCHEMBL23958627 | 0.77 | CFTR (0.36) | — | |
| SCHEMBL23958739 | 0.76 | TRPV3 (0.34) | — | |
| SCHEMBL23958778 | 0.74 | DGAT1 (0.33) | — | |
| SCHEMBL23958741 | 0.74 | TACR3 (0.35) | — | |
| SCHEMBL23958704 | 0.72 | CSNK1E (0.31) | — | |
| SCHEMBL23958871 | 0.72 | CSNK1E (0.31) | — | |
| SCHEMBL23958653 | 0.67 | CFTR (0.32) | MAPK1MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021214136-A1 | RSV INHIBITING 3-SUBSTITUTED QUINOLINE AND CINNOLINE DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2021-10-28 | — | — | WO | disclosed |