Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV3 | Q8NET8 | 4/20 | 0.34 |
| ▸ | PDE2A | O00408 | 4/20 | 0.32 |
| ▸ | CFTR | P13569 | 3/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.32 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.32 |
| ▸ | CKS1B | P61024 | 1/20 | 0.31 |
| ▸ | SKP1 | P63208 | 1/20 | 0.31 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.31 |
| ▸ | AXL | P30530 | 1/20 | 0.30 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.30 |
| ▸ | MERTK | Q12866 | 1/20 | 0.30 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.30 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23958587 | 0.82 | CFTR (0.34) | CFTR | |
| SCHEMBL23958793 | 0.79 | CFTR (0.35) | CFTRSLC34A1 | |
| SCHEMBL23958775 | 0.76 | ADRA1D (0.36) | PDE2ACFTRMDM2 | |
| SCHEMBL23958893 | 0.76 | MAPK1 (0.32) | — | |
| SCHEMBL23958627 | 0.75 | CFTR (0.36) | CFTRSLC34A1 | |
| SCHEMBL23958856 | 0.73 | PGR (0.30) | — | |
| SCHEMBL23958778 | 0.73 | DGAT1 (0.33) | — | |
| SCHEMBL23958756 | 0.72 | SLC34A1 (0.33) | SLC34A1 | |
| SCHEMBL23958709 | 0.71 | FFAR1 (0.31) | — | |
| SCHEMBL23958741 | 0.69 | TACR3 (0.35) | MERTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021214136-A1 | RSV INHIBITING 3-SUBSTITUTED QUINOLINE AND CINNOLINE DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2021-10-28 | — | — | WO | disclosed |