Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | TTR | P02766 | 1/20 | 0.45 |
| ▸ | EDNRA | P25101 | 2/20 | 0.43 |
| ▸ | EDNRB | P24530 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29915854 | 0.84 | CHEK1 (0.49) | TP53MAPTHPGDSMN1; SMN2KDM4E | |
| SCHEMBL9952138 | 0.84 | CHEK1 (0.49) | TP53MAPTHPGDSMN1; SMN2KDM4E | |
| SCHEMBL29915935 | 0.83 | MEN1 (0.52) | RAB9AMAPTHPGDSMN1; SMN2TTR | |
| SCHEMBL28735590 | 0.81 | MEN1 (0.46) | MAPTHPGDSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL23959045 | 0.81 | RAB9A (0.46) | RAB9AMAPTHPGDSMN1; SMN2KDM4E | |
| SCHEMBL23959070 | 0.81 | MEN1 (0.44) | MAPTSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL17583585 | 0.81 | GABRP (0.44) | MAPTHPGDSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL17583582 | 0.80 | TSHR (0.55) | MAPTHPGDSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL17583578 | 0.79 | SCN9A (0.44) | MAPTSMN1; SMN2KDM4EGAA | |
| SCHEMBL10368739 | 0.78 | HSD11B1 (0.45) | MAPTHPGDSMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021212974-A1 | RACEMIC AND CHIRAL 3-(2,3-BUTADIENYL)OXYINDOLINONE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 复旦大学 (CN) | 2021-10-28 | — | — | WO | disclosed |