Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | PARP1 | P09874 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | TNKS | O95271 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23959794 | 0.87 | SMN1; SMN2 (0.44) | TSHRSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL23959788 | 0.75 | KDM4E (0.53) | TSHRSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL23959779 | 0.75 | ALDH1A1 (0.52) | ALDH1A1MEN1KMT2ALMNAPARP1 | |
| SCHEMBL23959843 | 0.71 | ATM (0.42) | TSHRALDH1A1LMNAGAAKDM4E | |
| SCHEMBL23959783 | 0.69 | CYP1A2 (0.44) | TSHRSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL8503249 | 0.68 | TSHR (0.65) | TSHRSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL30311730 | 0.68 | TSHR (0.65) | TSHRSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL20102622 | 0.67 | KMT2A (0.82) | TSHRSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL7770196 | 0.66 | ALDH1A1 (0.86) | SMN1; SMN2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL6314431 | 0.63 | MEN1 (0.67) | ALDH1A1MEN1KMT2AGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210332038-A1 | 6H-IMIDAZO[4,5,1-ij]QUINOLONE, SYNTHESIS METHOD AND USE THEREOF | HANGZHOU NORMAL UNIVERSITY | 2021-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210332038-A1 | 6H-IMIDAZO[4,5,1-ij]QUINOLONE, SYNTHESIS METHOD AND USE THEREOF | ABL1, KCNK4, KCNJ4 | TSHR 2316/4885SMN1; SMN2 4559/4885ALDH1A1 1428/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.