Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HTR3A | P46098 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | GUSB | P08236 | 1/20 | 0.43 |
| ▸ | C1R | P00736 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | TDO2 | P48775 | 1/20 | 0.42 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.42 |
| ▸ | PDE2A | O00408 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23959772 | 0.75 | TSHR (0.50) | ALDH1A1PARP1KDM4EKMT2AMEN1 | |
| SCHEMBL23959788 | 0.74 | KDM4E (0.53) | ALDH1A1KDM4EKMT2AMEN1HPGD | |
| SCHEMBL23959794 | 0.74 | SMN1; SMN2 (0.44) | ALDH1A1KDM4EKMT2AMEN1HPGD | |
| SCHEMBL11009543 | 0.74 | KDM4E (0.75) | ALDH1A1KDM4EKMT2AMEN1HPGD | |
| SCHEMBL23959843 | 0.70 | ATM (0.42) | ALDH1A1KDM4ELMNAMAPK1GAA | |
| SCHEMBL5799528 | 0.68 | CASR (0.73) | ALDH1A1KDM4EKMT2AMEN1HPGD | |
| SCHEMBL7158035 | 0.67 | PARP1 (1.00) | PARP1HTR3A | |
| SCHEMBL5248590 | 0.66 | ALDH1A1 (0.63) | ALDH1A1KMT2AMEN1LMNAGAA | |
| SCHEMBL6980643 | 0.63 | KDM4E (0.42) | ALDH1A1KDM4EKMT2AMEN1HPGD | |
| SCHEMBL4395709 | 0.63 | LMNA (1.00) | ALDH1A1KDM4EKMT2AMEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210332038-A1 | 6H-IMIDAZO[4,5,1-ij]QUINOLONE, SYNTHESIS METHOD AND USE THEREOF | HANGZHOU NORMAL UNIVERSITY | 2021-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210332038-A1 | 6H-IMIDAZO[4,5,1-ij]QUINOLONE, SYNTHESIS METHOD AND USE THEREOF | ABL1, KCNK4, KCNJ4 | ALDH1A1 1428/4885PARP1 1358/4885KDM4E 621/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.