Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 3/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23959772 | 0.71 | TSHR (0.50) | ALDH1A1KDM4ETSHRGAALMNA | |
| SCHEMBL23959788 | 0.70 | KDM4E (0.53) | ALDH1A1KDM4EMAPK1HSD17B10L3MBTL1 | |
| SCHEMBL23959794 | 0.70 | SMN1; SMN2 (0.44) | ATMALDH1A1KDM4ETSHRLMNA | |
| SCHEMBL23959779 | 0.70 | ALDH1A1 (0.52) | ALDH1A1KDM4EMAPK1GAALMNA | |
| SCHEMBL3700186 | 0.65 | ATM (0.86) | ATMALDH1A1KDM4EMAPK1HSD17B10 | |
| SCHEMBL11482703 | 0.63 | PAX8 (0.39) | ALDH1A1HSD17B10TSHR | |
| SCHEMBL8583668 | 0.62 | NPC1 (0.37) | ALDH1A1KDM4EMAPK1HSD17B10L3MBTL1 | |
| SCHEMBL18387317 | 0.61 | ALDH1A1 (0.35) | ALDH1A1KDM4ETSHRLMNAHTT | |
| SCHEMBL6980643 | 0.60 | KDM4E (0.42) | ATMALDH1A1KDM4EMAPK1HSD17B10 | |
| SCHEMBL2509534 | 0.60 | CNR2 (0.40) | ALDH1A1CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210332038-A1 | 6H-IMIDAZO[4,5,1-ij]QUINOLONE, SYNTHESIS METHOD AND USE THEREOF | HANGZHOU NORMAL UNIVERSITY | 2021-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210332038-A1 | 6H-IMIDAZO[4,5,1-ij]QUINOLONE, SYNTHESIS METHOD AND USE THEREOF | ABL1, KCNK4, KCNJ4 | ATM 979/4885ALDH1A1 1428/4885KDM4E 621/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.