Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16613197 | 0.73 | ALDH1A1 (0.46) | CYP1A2POLBCYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL1462814 | 0.69 | KCNH2 (0.60) | CYP1A2POLBCYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL9034743 | 0.69 | TUBB4A (0.47) | CYP1A2POLBCYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL23959772 | 0.69 | TSHR (0.50) | CYP2C9CYP2C19ALDH1A1NPSR1RAB9A | |
| SCHEMBL1463663 | 0.68 | KCNH2 (0.59) | CYP1A2POLBCYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL13325842 | 0.66 | TNK2 (0.47) | POLBALDH1A1NPSR1KDM4EMEN1 | |
| SCHEMBL6306921 | 0.65 | F11 (0.63) | POLBALDH1A1EGFRKDM4EMEN1 | |
| SCHEMBL23959794 | 0.65 | SMN1; SMN2 (0.44) | POLBALDH1A1RAB9AKDM4EMEN1 | |
| SCHEMBL1317721 | 0.64 | KDM4E (0.61) | CYP1A2POLBCYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL31277481 | 0.63 | ALDH1A1 (0.95) | CYP1A2POLBCYP2C9CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210332038-A1 | 6H-IMIDAZO[4,5,1-ij]QUINOLONE, SYNTHESIS METHOD AND USE THEREOF | HANGZHOU NORMAL UNIVERSITY | 2021-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210332038-A1 | 6H-IMIDAZO[4,5,1-ij]QUINOLONE, SYNTHESIS METHOD AND USE THEREOF | ABL1, KCNK4, KCNJ4 | CYP1A2 239/4885POLB 3695/4885CYP2C9 257/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.