Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 10/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | BCR | P11274 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 2/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ACACA | Q13085 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13060384 | 0.82 | KIF11 (0.62) | KIF11KCNH2SMN1; SMN2 | |
| SCHEMBL462675 | 0.82 | KIF11 (0.62) | KIF11KCNH2SMN1; SMN2 | |
| SCHEMBL9713890 | 0.76 | BACE1 (0.48) | KIF11KCNH2ABL1ABCB1BCR | |
| SCHEMBL23960484 | 0.76 | ABL1 (0.42) | KIF11KCNH2ABL1ABCB1BCR | |
| SCHEMBL9729522 | 0.74 | BACE1 (0.50) | KIF11KCNH2ABL1ABCB1BCR | |
| SCHEMBL13336381 | 0.71 | PIN1 (0.47) | ABL1ABCB1BCRBACE1SMN1; SMN2 | |
| SCHEMBL8592606 | 0.71 | KIF11 (0.60) | KIF11KCNH2SMN1; SMN2 | |
| SCHEMBL5838167 | 0.71 | KIF11 (0.60) | KIF11KCNH2SMN1; SMN2 | |
| SCHEMBL27845746 | 0.70 | PIN1 (0.46) | ABL1ABCB1BCRBACE1SMN1; SMN2 | |
| SCHEMBL15212173 | 0.70 | KIF11 (0.68) | KIF11KCNH2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210332070-A1 | Compositions and Methods for Synthesis of Phosphorylated Molecules | UNIV CALIFORNIA (US) | 2021-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210332070-A1 | Compositions and Methods for Synthesis of Phosphorylated Molecules | PIK3CA, CHAMP1, TYMP | KIF11 2519/4885KCNH2 3514/4885ABL1 387/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.