Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 3/20 | 0.50 |
| ▸ | KIF11 | P52732 | 5/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | BCR | P11274 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.37 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | BCL2 | P10415 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9713951 | 0.80 | KIF11 (0.47) | BACE1KIF11KCNH2ESR1ABL1 | |
| SCHEMBL15212173 | 0.75 | KIF11 (0.68) | KIF11KCNH2ALDH1A1MEN1KMT2A | |
| SCHEMBL23960443 | 0.74 | KIF11 (0.46) | BACE1KIF11KCNH2ABL1ABCB1 | |
| SCHEMBL9713939 | 0.73 | KIF11 (0.51) | BACE1KIF11KCNH2ESR1CNR1 | |
| SCHEMBL9713821 | 0.72 | CNR1 (0.50) | BACE1KIF11KCNH2CNR1CNR2 | |
| SCHEMBL9713890 | 0.72 | BACE1 (0.48) | BACE1KIF11KCNH2ABL1ABCB1 | |
| SCHEMBL10772494 | 0.71 | MMP3 (0.54) | KIF11ESR1ALDH1A1MEN1KMT2A | |
| SCHEMBL9713613 | 0.70 | THRA (0.39) | BACE1KIF11KCNH2ESR1CNR1 | |
| SCHEMBL28076878 | 0.70 | KIF11 (0.55) | KIF11KCNH2ALDH1A1MEN1KMT2A | |
| SCHEMBL28076876 | 0.70 | KIF11 (0.55) | KIF11KCNH2ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5151531-A | DIHYDRIC PHENOLS | IDEMITSU KOSAN CO., LTD. (JP) | 1992-09-29 | — | — | US | disclosed |