Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 5/20 | 0.48 |
| ▸ | KIF11 | P52732 | 3/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.40 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | BCR | P11274 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9713951 | 0.90 | KIF11 (0.47) | BACE1KIF11KCNH2KDM4EMAPT | |
| SCHEMBL9713495 | 0.89 | NPC1 (0.40) | BACE1POLBNPC1RAB9A | |
| SCHEMBL2859474 | 0.89 | BACE1 (0.47) | BACE1KIF11CNR1CNR2 | |
| SCHEMBL9817006 | 0.88 | LMNA (0.44) | BACE1KIF11KDM4ESMN1; SMN2CNR1 | |
| SCHEMBL9713939 | 0.87 | KIF11 (0.51) | BACE1KIF11KCNH2KDM4EMAPT | |
| SCHEMBL9713821 | 0.86 | CNR1 (0.50) | BACE1KIF11KCNH2KDM4EMAPT | |
| SCHEMBL9816992 | 0.86 | HDAC8 (0.41) | BACE1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL9816990 | 0.85 | KIF11 (0.43) | BACE1KIF11CNR1CNR2 | |
| SCHEMBL9817035 | 0.83 | BACE1 (0.53) | BACE1KDM4EMAPTSMN1; SMN2MAPK1 | |
| SCHEMBL9713478 | 0.82 | ESR1 (0.51) | BACE1KDM4EMAPTSMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5151531-A | DIHYDRIC PHENOLS | IDEMITSU KOSAN CO., LTD. (JP) | 1992-09-29 | — | — | US | disclosed |
| EP-0249963-B1 | POLYCARBONATES | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1992-04-22 | — | — | EP | disclosed |
| EP-0277627-B1 | POLYFORMAL RESINS AND PROCESS FOR PRODUCING SAID RESINS | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1991-10-23 | — | — | EP | disclosed |
| US-4892924-A | Polycarbonate containing compound from bis(3-phenyl-4-hydroxyphenyl) | IDEMITSU KOSAN CO., LTD. (JP) | 1990-01-09 | — | — | US | disclosed |
| US-4801679-A | Polyformal resin and process for producing said resin | IDEMITSU KOSAN CO., LTD. (JP) | 1989-01-31 | — | — | US | disclosed |
| EP-0277627-A1 | Polyformal resins and process for producing said resins | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1988-08-10 | — | — | EP | disclosed |
| EP-0249963-A2 | Polycarbonates | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1987-12-23 | — | — | EP | disclosed |