Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 3/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | IAPP | P10997 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23964561 | 0.91 | CA2 (0.47) | CA2HTR1AGABRA1GABRB2ATM | |
| SCHEMBL7065972 | 0.81 | CA2 (0.59) | CA2GABRA1GABRB2ATMALOX12 | |
| SCHEMBL7944832 | 0.80 | ALDH1A1 (0.48) | CA2GABRA1GABRB2ATMALOX12 | |
| SCHEMBL57139 | 0.79 | GABRA1 (0.67) | CA2GABRA1GABRB2ATMALOX12 | |
| SCHEMBL2208339 | 0.78 | CA2 (0.55) | CA2GABRA1GABRB2ATMALOX12 | |
| SCHEMBL3809080 | 0.78 | CA2 (0.59) | CA2GABRA1GABRB2ATMALOX12 | |
| Propane SCHEMBL28225674 | 0.77 | GABRA1 (0.64) | CA2GABRA1GABRB2ATMALOX12 | |
| SCHEMBL8319104 | 0.77 | ALOX5 (0.57) | CA2GABRA1GABRB2ATMIAPP | |
| SCHEMBL430927 | 0.76 | CA2 (0.57) | CA2GABRA1GABRB2ATMALOX12 | |
| SCHEMBL9994746 | 0.75 | CA2 (0.61) | CA2GABRA1GABRB2ATMALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11155547-B1 | Compounds for and methods of treating diseases | Alterity Therapeutics Limited (AU) | 2021-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11155547-B1 | Compounds for and methods of treating diseases | HTT, SNCA, PARK7 | CA2 1650/4885HTR1A 668/4885GABRA1 3643/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.