Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | F2R | P25116 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23964432 | 0.92 | MEN1 (0.49) | SIGMAR1POLBKMT2AMEN1CYP2D6 | |
| SCHEMBL15306596 | 0.86 | SIGMAR1 (0.57) | SIGMAR1POLBKMT2AMEN1CYP2D6 | |
| SCHEMBL24127975 | 0.82 | POLB (0.51) | SIGMAR1POLBKMT2AMEN1CYP2D6 | |
| SCHEMBL23964437 | 0.78 | ALDH1A1 (0.50) | SIGMAR1POLBCYP2D6TSHRCA2 | |
| SCHEMBL23926337 | 0.76 | SIGMAR1 (0.48) | SIGMAR1POLBKMT2AMEN1CYP2D6 | |
| SCHEMBL23926333 | 0.76 | SIGMAR1 (0.61) | SIGMAR1POLBKMT2AMEN1TSHR | |
| SCHEMBL1264054 | 0.74 | SIGMAR1 (0.52) | SIGMAR1POLBKMT2AMEN1CYP2D6 | |
| SCHEMBL2208339 | 0.74 | CA2 (0.55) | CA2 | |
| SCHEMBL6567771 | 0.74 | CA2 (0.55) | TSHRCA2CYP2C9NPSR1ALDH1A1 | |
| SCHEMBL5323909 | 0.73 | HRH3 (0.54) | SIGMAR1POLBKMT2AMEN1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11155547-B1 | Compounds for and methods of treating diseases | Alterity Therapeutics Limited (AU) | 2021-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11155547-B1 | Compounds for and methods of treating diseases | HTT, SNCA, PARK7 | SIGMAR1 3913/4885POLB 2864/4885KMT2A 730/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.