SCHEMBL23965634

SCHEMBL23965634

COCc1ccccc1/C(C)=N/OCc1c(C)cccc1C(=N)C(=O)CCC(C)C

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
P2RX7 Q99572 1/20 0.35
KCNA5 P22460 2/20 0.33
HIF1A Q16665 2/20 0.32
HDAC3 O15379 1/20 0.32
HDAC1 Q13547 1/20 0.32
PRMT5 O14744 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23965638 0.84 HIF1A (0.39) HIF1AHDAC3HDAC1PRMT5
SCHEMBL23972106 0.75 HIF1A (0.52) HIF1APRMT5
SCHEMBL23965681 0.74 KCNK3 (0.34) HIF1A
SCHEMBL23971864 0.74 HIF1A (0.41) HIF1APRMT5
SCHEMBL23965639 0.73 P2RX7 (0.39) P2RX7KCNA5
SCHEMBL23972114 0.71 HIF1A (0.47) KCNA5HIF1A
SCHEMBL23972104 0.71 HIF1A (0.33) HIF1APRMT5
SCHEMBL23972095 0.70 HIF1A (0.38) KCNA5HIF1A
SCHEMBL23972077 0.68 HIF1A (0.50) HIF1A
SCHEMBL23969505 0.68 TSHR (0.35) HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3903582-A1 USE OF STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI CONTAINING AN AMINO ACID SUBSTITUTION F129L IN THE MITOCHONDRIAL CYTOCHROME B PROTEIN CONFERRING RESISTANCE TO QO INHIBITORS II BASF SE (DE) 2021-11-03 EP disclosed
EP-3903583-A1 USE OF STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI CONTAINING AN AMINO ACID SUBSTITUTION F129L IN THE MITOCHONDRIAL CYTOCHROME B PROTEIN CONFERRING RESISTANCE TO QO INHIBITORS III BASF SE (DE) 2021-11-03 EP disclosed