Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 10/20 | 0.63 |
| ▸ | RHEB | Q15382 | 3/20 | 0.38 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23966818 | 0.92 | S1PR2 (0.65) | S1PR2RHEBCYP3A4CYP2C9 | |
| SCHEMBL23908839 | 0.91 | S1PR2 (0.75) | S1PR2RHEB | |
| SCHEMBL23914704 | 0.90 | S1PR2 (0.62) | S1PR2RHEBCCNE2CCNE1CDK2 | |
| SCHEMBL23966844 | 0.85 | S1PR2 (0.70) | S1PR2RHEBCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL23908779 | 0.85 | S1PR2 (0.65) | S1PR2RHEBMEN1KMT2AMAPT | |
| SCHEMBL23966848 | 0.78 | S1PR2 (0.72) | S1PR2RHEB | |
| SCHEMBL23966530 | 0.77 | S1PR2 (0.82) | S1PR2CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL23966542 | 0.75 | S1PR2 (0.82) | S1PR2CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL23966552 | 0.75 | S1PR2 (0.84) | S1PR2RHEB | |
| SCHEMBL23908887 | 0.74 | S1PR2 (0.94) | S1PR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3649119-B1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS | GALAPAGOS NV (BE) | 2021-11-03 | — | — | EP | disclosed |