Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 13/20 | 0.40 |
| ▸ | PGK1 | P00558 | 1/20 | 0.35 |
| ▸ | PGK2 | P07205 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
| ▸ | IDH2 | P48735 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23967218 | 0.80 | IDH1 (0.37) | PGK1PGK2ADRB1IDH1IDH2 | |
| SCHEMBL15832228 | 0.80 | HTR3E (0.35) | PGK1PGK2 | |
| SCHEMBL25568031 | 0.80 | PGK1 (0.35) | PGK1PGK2ADRB1IDH1IDH2 | |
| SCHEMBL15832235 | 0.79 | HSD11B1 (0.41) | HSD11B1PGK1PGK2NR1H3ADORA2A | |
| SCHEMBL17353809 | 0.78 | HSD11B1 (0.40) | HSD11B1PGK1PGK2NR1H3ADORA2A | |
| SCHEMBL23966993 | 0.76 | ADRB1 (0.32) | PGK1PGK2ADRB1 | |
| SCHEMBL12221318 | 0.76 | HTR3E (0.37) | IDH1IDH2 | |
| SCHEMBL30565508 | 0.76 | P2RX7 (0.43) | PGK1PGK2ADRB1IDH1IDH2 | |
| SCHEMBL12153223 | 0.76 | P2RX7 (0.43) | PGK1PGK2ADRB1IDH1IDH2 | |
| SCHEMBL21790630 | 0.75 | ADORA2A (0.42) | HSD11B1PGK1PGK2NR1H3ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3572413-B1 | 1,2-DIHYDRO-3H-PYRAZOLO[3,4-D]PYRIMIDIN-3-ONE DERIVATIVE AS WEE1 INHIBITOR | SHIJIAZHUANG SAGACITY NEW DRUG DEV CO LTD (CN) | 2021-11-03 | — | — | EP | disclosed |