SCHEMBL23967782

SCHEMBL23967782

CC(C)(C)c1cccc2c1sc1c(I)cccc12

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.38
KIF11 P52732 1/20 0.36
GABRA1 P14867 1/20 0.33
GABRB2 P47870 1/20 0.33
ALDH1A1 P00352 1/20 0.32
TSHR P16473 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
PDE10A Q9Y233 1/20 0.31
F9 P00740 1/20 0.30
F10 P00742 1/20 0.30
PLAU P00749 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21111350 0.88 CA2 (0.46) CA2KIF11GABRA1GABRB2ALDH1A1
SCHEMBL357116 0.82 PLAU (0.34) PDE10AF9F10PLAU
SCHEMBL24422197 0.79 GABRA1 (0.47) CA2KIF11GABRA1GABRB2ALDH1A1
SCHEMBL12395340 0.77 GPR3 (0.50) CA2KIF11ALDH1A1TSHRTDP1
SCHEMBL26362310 0.76 CA2 (0.36) CA2KIF11GABRA1GABRB2ALDH1A1
SCHEMBL16282355 0.75 CYP1A1 (0.43) CA2KIF11ALDH1A1TSHRTDP1
SCHEMBL24809426 0.75 KIF11 (0.38) KIF11ALDH1A1TDP1F9F10
SCHEMBL18818728 0.75 CYP2A6 (0.42) CA2KIF11ALDH1A1TSHRPDE10A
SCHEMBL16282382 0.74 LIMK1 (0.46) CA2KIF11ALDH1A1TSHRTDP1
SCHEMBL20650237 0.74 KIF11 (0.34) CA2KIF11ALDH1A1TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3428152-B1 COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME LG CHEMICAL LTD (KR) 2021-11-03 EP disclosed