SCHEMBL357116

SCHEMBL357116

Ic1cccc2c1sc1c(I)cccc12

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PLAU P00749 2/20 0.34
F9 P00740 1/20 0.34
F10 P00742 1/20 0.34
PDE10A Q9Y233 1/20 0.34
DYRK1A Q13627 1/20 0.33
GPR3 P46089 1/20 0.33
NOS1 P29475 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18818728 0.87 CYP2A6 (0.42) PDE10A
SCHEMBL17207338 0.87 AHR (0.36) PDE10ADYRK1A
SCHEMBL355686 0.84 GPR3 (0.54) PLAUF9F10GPR3
SCHEMBL23967782 0.82 CA2 (0.38) PLAUF9F10PDE10A
SCHEMBL20650733 0.82 DYRK1A (0.47) PDE10ADYRK1A
SCHEMBL20650209 0.82 GABRA1 (0.38) PDE10A
SCHEMBL18435928 0.82 LIMK1 (0.49) F9DYRK1A
SCHEMBL18435736 0.79 LIMK1 (0.47) F9DYRK1A
SCHEMBL18910348 0.79
SCHEMBL23967774 0.78 KDM4E (0.36) DYRK1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023085047-A1 ORGANIC LIGHT EMITTING ELEMENT キヤノン株式会社 2023-05-19 WO disclosed
US-9997726-B2 Dibenzothiophene-containing materials in phosphorescent light emitting diodes UNIVERSAL DISPLAY CORPORATION (US) 2018-06-12 US disclosed
US-20160372685-A1 Dibenzothiophene-Containing Materials in Phosphorescent Light Emitting Diodes UNIVERSAL DISPLAY CORPORATION (US) 2016-12-22 US disclosed
US-20160155955-A1 DICARBAZOLE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT DEVICES HODOGAYA CHEMICAL CO., LTD. (JP) 2016-06-02 US disclosed
EP-3009438-A1 DICARBAZOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2016-04-20 EP disclosed
CN-105452255-A Dicarbazole derivative and organic electroluminescent element HODOGAYA CHEMICAL CO LTD 2016-03-30 CN disclosed
US-9190620-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2015-11-17 US disclosed
US-9190620-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2015-11-17 US disclosed
US-9190620-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2015-11-17 US disclosed
US-20150249221-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-09-03 US disclosed
US-8743031-B2 Dibenzothiophene compound and organic light-emitting element based on the same CANON KABUSHIKI KAISHA (JP) 2014-06-03 US disclosed
US-8743031-B2 Dibenzothiophene compound and organic light-emitting element based on the same CANON KABUSHIKI KAISHA (JP) 2014-06-03 US disclosed
US-20140008643-A1 DIBENZOTHIOPHENE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2014-01-09 US disclosed
US-8580402-B2 Dibenzothiophene-containing materials in phosphorescent light emitting diodes UNIVERSAL DISPLAY CORPORATION (US) 2013-11-12 US disclosed
US-20120075171-A1 DIBENZOTHIOPHENE COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT BASED ON THE SAME CANON KABUSHIKI KAISHA (JP) 2012-03-29 US disclosed
US-20120075171-A1 DIBENZOTHIOPHENE COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT BASED ON THE SAME CANON KABUSHIKI KAISHA (JP) 2012-03-29 US disclosed
US-20120012829-A1 DIBENZOTHIOPHENE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2012-01-19 US disclosed
US-8007927-B2 Dibenzothiophene-containing materials in phosphorescent light emitting diodes UNIVERSAL DISPLAY CORPORATION (US) 2011-08-30 US disclosed
WO-2009085344-A2 DIBENZOTHIOPHENE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2009-07-09 WO disclosed
US-20090167162-A1 DIBENZOTHIOPHENE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2009-07-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160155955-A1 DICARBAZOLE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT DEVICES AHR, NAT1, NR2C2 PLAU 4369/4885F9 3463/4885F10 2829/4885
US-20090167162-A1 DIBENZOTHIOPHENE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTING DIODES DDT, BPNT1, DBF4 PLAU 3678/4885F9 3739/4885F10 4143/4885
US-20120075171-A1 DIBENZOTHIOPHENE COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT BASED ON THE SAME TPT1, RFT1, ARNT PLAU 4828/4885F9 3549/4885F10 3063/4885
US-20150249221-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES DDT, TERF2, DBF4 PLAU 1545/4885F9 3584/4885F10 3293/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.