SCHEMBL23967795

SCHEMBL23967795

CN(c1ccccc1C(C)(C)C)c1cccc2c1oc1c(S(C)(C)C)cccc12

nearest known ligand 0.31

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2C19 P33261 1/20 0.31
HTT P42858 1/20 0.31
HIF1A Q16665 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
CA2 P00918 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20172831 0.87 KIF11 (0.35) KIF11CYP2C19TDP1CA2
SCHEMBL20172798 0.83 GABRA1 (0.37) KIF11CA2
SCHEMBL20172807 0.82 KIF11 (0.32) KIF11
SCHEMBL20172842 0.82 ACP1 (0.33) KIF11CYP1A2CYP2C19
SCHEMBL20172783 0.82 KMT2A (0.43) KIF11CYP2C19HTTL3MBTL1CA2
SCHEMBL20172857 0.81 KIF11 (0.31) KIF11
SCHEMBL21019993 0.80 SIGMAR1 (0.33) KIF11CYP2C19
SCHEMBL21021447 0.80 ALOX5 (0.33) KIF11CYP1A2CYP2C19HTTHIF1A
SCHEMBL20172828 0.80 ACP1 (0.33) KIF11CYP1A2CYP2C19
SCHEMBL20172818 0.79 ALDH1A1 (0.38) KIF11HTTCA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3428152-B1 COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME LG CHEMICAL LTD (KR) 2021-11-03 EP disclosed