Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 11/20 | 0.45 |
| ▸ | PPARG | P37231 | 2/20 | 0.45 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.42 |
| ▸ | PCSK9 | Q8NBP7 | 2/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | VCP | P55072 | 3/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16069689 | 0.87 | FFAR1 (0.49) | FFAR1PPARGCYP1A1PCSK9FFAR4 | |
| SCHEMBL17402604 | 0.74 | HAVCR2 (0.39) | — | |
| SCHEMBL17402605 | 0.73 | CNR2 (0.37) | FFAR1 | |
| SCHEMBL23967852 | 0.73 | PRKAG1 (0.45) | FFAR1PPARG | |
| SCHEMBL17402637 | 0.72 | PRKAB2 (0.45) | FFAR1 | |
| SCHEMBL17402602 | 0.72 | PTGS2 (0.41) | — | |
| SCHEMBL23967861 | 0.71 | KMT2A (0.38) | MAPT | |
| SCHEMBL17402603 | 0.71 | PRKAG1 (0.40) | MAPT | |
| SCHEMBL23967636 | 0.69 | KDM4A (0.40) | — | |
| SCHEMBL864817 | 0.69 | PCSK9 (0.56) | CYP1A1PCSK9IDO1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970119-B1 | NOVEL INDOLE DERIVATIVES USEFUL AS ANTI-DIABETIC AGENTS | MERCK SHARP & DOHME (US) | 2021-11-03 | — | — | EP | disclosed |