Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 4/20 | 0.35 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8572776 | 0.82 | DNM1 (0.37) | DNM1BBOX1 | |
| Hydrochloric Acid SCHEMBL718779 | 0.80 | ACHE (0.50) | DNM1BBOX1TSHRTDP1 | |
| SCHEMBL7651543 | 0.79 | DNM1 (0.44) | DNM1BBOX1TSHR | |
| SCHEMBL1568811 | 0.78 | ACHE (0.52) | BBOX1TSHRTDP1 | |
| Hydrogen Sulfide SCHEMBL27823450 | 0.77 | CES1 (0.46) | TSHRTDP1 | |
| SCHEMBL164095 | 0.74 | — | — | |
| SCHEMBL731106 | 0.73 | TDP1 (0.40) | TDP1 | |
| SCHEMBL10901940 | 0.73 | TDP1 (0.40) | TSHRTDP1 | |
| SCHEMBL1082359 | 0.73 | CES2 (0.50) | TSHRTDP1 | |
| Hydrochloric Acid SCHEMBL15846838 | 0.73 | CES1 (0.46) | TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110230619-A1 | Nitrogen-Containing Organosilicon Graft Copolymers | EVONIK GOLDSCHMIDT GMBH (DE) | 2011-09-22 | — | — | US | claimed |
| US-20120202959-A1 | Process for Producing Water-Absorbing Polymer Particles | BASF SE (DE) | 2012-08-09 | — | — | US | disclosed |
| US-20110257340-A1 | Process for Producing Water-Absorbing Polymer Particles | BASF SE (DE) | 2011-10-20 | — | — | US | disclosed |
| US-20110230619-A1 | Nitrogen-Containing Organosilicon Graft Copolymers | EVONIK GOLDSCHMIDT GMBH (DE) | 2011-09-22 | — | — | US | disclosed |