Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 4/20 | 0.37 |
| ▸ | CES2 | O00748 | 3/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23969673 | 0.81 | ATM (0.37) | CES1CES2MTNR1AMTNR1BATM | |
| SCHEMBL3590417 | 0.69 | ALDH1A1 (0.43) | CES1CES2MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL15969889 | 0.68 | TDP1 (0.43) | CES1CES2ALDH1A1HPGDRAB9A | |
| SCHEMBL22109788 | 0.67 | ATM (0.40) | CES1CES2MTNR1AMTNR1BATM | |
| SCHEMBL23845906 | 0.67 | CES2 (0.47) | CES1CES2ATMALDH1A1HPGD | |
| SCHEMBL28533849 | 0.66 | ALDH1A1 (0.40) | CES1CES2MTNR1AMTNR1BATM | |
| SCHEMBL11639951 | 0.65 | NFE2L2 (0.55) | CES1CES2ALDH1A1HPGDRAB9A | |
| SCHEMBL11639953 | 0.65 | NFE2L2 (0.55) | CES1CES2ALDH1A1HPGDRAB9A | |
| SCHEMBL23969709 | 0.65 | ATM (0.35) | MTNR1AMTNR1BATMALDH1A1HPGD | |
| SCHEMBL22037150 | 0.65 | ERCC5 (0.36) | ALDH1A1HPGDRAB9AMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3904366-A1 | END CAPPED NUCLEIC ACID MOLECULES | Novartis AG (CH) | 2021-11-03 | — | — | EP | disclosed |