Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 3/20 | 0.67 |
| ▸ | CHKA | P35790 | 6/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | LPL | P06858 | 2/20 | 0.43 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.43 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.42 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.42 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.42 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14059717 | 0.85 | ENPP2 (0.76) | ENPP2CA2LPLLIPGORAI1 | |
| SCHEMBL28166 | 0.82 | ENPP2 (1.00) | ENPP2CA2LPLLIPGORAI1 | |
| SCHEMBL5213200 | 0.82 | CHKA (0.55) | CHKATSHRALDH1A1POLBTDP1 | |
| Ethane SCHEMBL6986774 | 0.79 | CHKA (0.53) | CHKATSHRALDH1A1POLBTDP1 | |
| SCHEMBL27648777 | 0.79 | ENPP2 (0.94) | ENPP2CA2LPLLIPGORAI1 | |
| Hydrochloric Acid SCHEMBL6414496 | 0.79 | CHKA (0.53) | CHKATSHRALDH1A1POLBTDP1 | |
| SCHEMBL28117303 | 0.79 | ENPP2 (0.94) | ENPP2CA2LPLLIPGORAI1 | |
| SCHEMBL26745046 | 0.78 | ENPP2 (0.64) | ENPP2CA2LPLLIPGORAI1 | |
| SCHEMBL3845008 | 0.76 | PGR (0.57) | ENPP2CA2CA1ALDH1A1 | |
| SCHEMBL11160853 | 0.76 | PTGS2 (0.54) | CHKAALDH1A1POLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120004244-A1 | Bis Aromatic Compounds for Use as LTC4 Synthase Inhibitors | BIOLIPOX AB (SW) | 2012-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120004244-A1 | Bis Aromatic Compounds for Use as LTC4 Synthase Inhibitors | LTC4S, LTB4R2, LTB4R | ENPP2 178/4885CHKA 3910/4885CA2 2545/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.