Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.43 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4759808 | 0.82 | TBXAS1 (0.44) | RAB9ABAZ2BBAZ2ALMNAALDH1A1 | |
| SCHEMBL4759807 | 0.82 | TBXAS1 (0.44) | RAB9ABAZ2BBAZ2ALMNAALDH1A1 | |
| SCHEMBL3387788 | 0.81 | HDAC8 (0.51) | ALDH1A1HDAC8KMT2AKDM4E | |
| SCHEMBL2729849 | 0.80 | RAB9A (0.51) | RAB9ABAZ2BBAZ2ALMNAALDH1A1 | |
| SCHEMBL12096990 | 0.77 | HDAC8 (0.41) | ALDH1A1HDAC8 | |
| SCHEMBL14799952 | 0.77 | RAB9A (0.49) | RAB9ABAZ2BBAZ2ALMNAALDH1A1 | |
| SCHEMBL5121029 | 0.77 | RAB9A (0.49) | RAB9ABAZ2BBAZ2ALMNAALDH1A1 | |
| SCHEMBL1441399 | 0.75 | HDAC8 (0.47) | ALDH1A1HDAC8KMT2AKDM4EAR | |
| SCHEMBL16403997 | 0.75 | RAB9A (0.48) | RAB9ABAZ2BBAZ2ALMNAALDH1A1 | |
| SCHEMBL1126661 | 0.75 | P2RY12 (0.51) | RAB9ALMNAALDH1A1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1713838-A2 | METHOD FOR PRODUCING POLYISOBUTENYLPHENOLS | BASF AKTIENGESELLSCHAFT (DE) | 2006-10-25 | — | — | EP | claimed |
| WO-2005073152-A2 | METHOD FOR PRODUCING POLYISOBUTENYLPHENOLS | BASF AKTIENGESELLSCHAFT (DE) | 2005-08-11 | — | — | WO | claimed |
| EP-2066627-B1 | NOVEL MINOR GROOVE BINDERS | UNIV STRATHCLYDE (GB) | 2013-10-23 | — | — | EP | disclosed |
| US-8012967-B2 | Minor groove binders | UNIVERSITY OF STRATHCLYDE (GB) | 2011-09-06 | — | — | US | disclosed |
| US-20100016311-A1 | NOVEL MINOR GROOVE BINDERS | UNIVERSITY OF STRATHCLYDE (GB) | 2010-01-21 | — | — | US | disclosed |
| EP-2066627-A1 | NOVEL MINOR GROOVE BINDERS | The University of Strathclyde (GB) | 2009-06-10 | — | — | EP | disclosed |
| WO-2008038018-A1 | NOVEL MINOR GROOVE BINDERS | UNIVERSITY OF STRATHCLYDE (GB) | 2008-04-03 | — | — | WO | disclosed |
| EP-1360176-B1 | PYRROLECARBOXAMIDES FOR USE AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2006-11-02 | — | — | EP | disclosed |
| EP-1713838-A2 | METHOD FOR PRODUCING POLYISOBUTENYLPHENOLS | BASF AKTIENGESELLSCHAFT (DE) | 2006-10-25 | — | — | EP | disclosed |
| WO-2005073152-A2 | METHOD FOR PRODUCING POLYISOBUTENYLPHENOLS | BASF AKTIENGESELLSCHAFT (DE) | 2005-08-11 | — | — | WO | disclosed |
| US-20040082477-A1 | Pyrrolecarboxamides for the use as fungicdes | SYNGENTA CROP PROTECTION, INC. | 2004-04-29 | — | — | US | disclosed |
| EP-1360176-A1 | PYRROLECARBOXAMIDES FOR USE AS FUNGICIDES | Syngenta Participations AG (CH) | 2003-11-12 | — | — | EP | disclosed |
| WO-2002064562-A1 | PYRROLECARBOXAMIDES FOR THE USE AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2002-08-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016311-A1 | NOVEL MINOR GROOVE BINDERS | TOP2B, DNA2, CTCF | RAB9A 2181/4885BAZ2B 236/4885BAZ2A 603/4885 |
| US-20040082477-A1 | Pyrrolecarboxamides for the use as fungicdes | CBR3, HPD, BROX | RAB9A 2940/4885BAZ2B 200/4885BAZ2A 316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.