Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28701143 | 0.81 | MEN1 (0.57) | SMN1; SMN2KDM4EMEN1KMT2APKM | |
| SCHEMBL20306077 | 0.79 | ALDH1A1 (0.55) | SMN1; SMN2CHRNB2CHRNA5CHRNA7CHRNA4 | |
| SCHEMBL19943730 | 0.78 | ALDH1A1 (0.45) | SMN1; SMN2CHRNB2CHRNA5CHRNA7CHRNA4 | |
| SCHEMBL19186103 | 0.76 | RAB9A (0.47) | SMN1; SMN2CHRNB2CHRNA5CHRNA7CHRNA4 | |
| SCHEMBL20306078 | 0.75 | KMT2A (0.44) | CHRNB2CHRNA5CHRNA7CHRNA4CARM1 | |
| SCHEMBL25629349 | 0.74 | KMT2A (0.47) | CHRNB2CHRNA5CHRNA7CHRNA4CARM1 | |
| SCHEMBL27889142 | 0.73 | KMT2A (0.45) | CHRNB2CHRNA5CHRNA7CHRNA4CARM1 | |
| SCHEMBL18533749 | 0.73 | CHRNA7 (0.43) | CHRNB2CHRNA5CHRNA7CHRNA4CARM1 | |
| SCHEMBL27312954 | 0.72 | TSHR (0.45) | SMN1; SMN2CHRNB2CHRNA5CHRNA7CHRNA4 | |
| SCHEMBL18821943 | 0.72 | KMT2A (0.46) | CHRNB2CHRNA5CHRNA7CHRNA4CARM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210340176-A1 | Compounds | ATHIRA PHARMA, INC. (US) | 2021-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210340176-A1 | Compounds | BACE1, BDNF, CLN6 | SMN1; SMN2 21/4885CHRNB2 864/4885CHRNA5 1100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.