Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN7 | P35236 | 6/20 | 1.00 |
| ▸ | DUSP3 | P51452 | 6/20 | 1.00 |
| ▸ | PTPN22 | Q9Y2R2 | 4/20 | 1.00 |
| ▸ | PTPN12 | Q05209 | 3/20 | 1.00 |
| ▸ | DUSP6 | Q16828 | 2/20 | 0.91 |
| ▸ | MEN1 | O00255 | 9/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.72 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.69 |
| ▸ | BLM | P54132 | 2/20 | 0.67 |
| ▸ | DNMT1 | P26358 | 2/20 | 0.66 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.60 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2398377 | 1.00 | PTPN7 (1.00) | PTPN7DUSP3PTPN22PTPN12DUSP6 | |
| SCHEMBL12267452 | 0.94 | PTPN7 (0.90) | PTPN7DUSP3PTPN22PTPN12DUSP6 | |
| SCHEMBL2397611 | 0.90 | PTPN7 (0.82) | PTPN7DUSP3PTPN22PTPN12DUSP6 | |
| SCHEMBL13855965 | 0.82 | ALDH1A1 (0.76) | PTPN7DUSP3PTPN22PTPN12DUSP6 | |
| SCHEMBL4669327 | 0.79 | MEN1 (0.69) | PTPN7DUSP3PTPN22PTPN12DUSP6 | |
| SCHEMBL4669325 | 0.79 | MEN1 (0.69) | PTPN7DUSP3PTPN22PTPN12DUSP6 | |
| SCHEMBL13855903 | 0.79 | DUSP3 (0.65) | PTPN7DUSP3PTPN22PTPN12DUSP6 | |
| SCHEMBL4670263 | 0.77 | ALDH1A1 (0.84) | PTPN7DUSP3PTPN22DUSP6MEN1 | |
| SCHEMBL4670262 | 0.77 | ALDH1A1 (0.84) | PTPN7DUSP3PTPN22DUSP6MEN1 | |
| SCHEMBL4669021 | 0.75 | MEN1 (1.00) | PTPN7DUSP3PTPN22PTPN12DUSP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110212974-A1 | METHOD FOR IDENTIFYING COMPOUNDS USEFUL FOR TREATING AND/OR PREVENTING DISEASE-ASSOCIATED BONE LOSS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) | 2011-09-01 | — | — | US | claimed |
| EP-2716285-B9 | Compounds for treating and/or preventing diseases associated with bone loss | CENTRE NAT DE LA RECH SCIENT -CNRS- (FR) | 2017-03-01 | — | — | EP | disclosed |
| EP-2716285-B1 | Compounds for treating and/or preventing diseases associated with bone loss | CENTRE NAT RECH SCIENT (FR) | 2016-04-27 | — | — | EP | disclosed |
| EP-2331967-B1 | NEW METHOD FOR IDENTIFYING COMPOUNDS USEFUL FOR TREATING AND/OR PREVENTING DISEASES ASSOCIATED WITH BONE LOSS | CENTRE NAT RECH SCIENT (FR) | 2015-11-04 | — | — | EP | disclosed |
| US-9091678-B2 | Method for identifying compounds useful for treating and/or preventing disease-associated bone loss | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2015-07-28 | — | — | US | disclosed |
| US-20110212974-A1 | METHOD FOR IDENTIFYING COMPOUNDS USEFUL FOR TREATING AND/OR PREVENTING DISEASE-ASSOCIATED BONE LOSS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) | 2011-09-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110212974-A1 | METHOD FOR IDENTIFYING COMPOUNDS USEFUL FOR TREATING AND/OR PREVENTING DISEASE-ASSOCIATED BONE LOSS | DOCK5, ARHGDIB, ARHGDIA | PTPN7 3264/4885DUSP3 611/4885PTPN22 3222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.