Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN7 | P35236 | 3/20 | 0.82 |
| ▸ | DUSP3 | P51452 | 3/20 | 0.82 |
| ▸ | PTPN12 | Q05209 | 2/20 | 0.82 |
| ▸ | PTPN22 | Q9Y2R2 | 2/20 | 0.82 |
| ▸ | DUSP6 | Q16828 | 1/20 | 0.76 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 9/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | PTGES | O14684 | 1/20 | 0.57 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.56 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.56 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.56 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.55 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2398377 | 0.90 | PTPN7 (1.00) | PTPN7DUSP3PTPN12PTPN22DUSP6 | |
| SCHEMBL2397608 | 0.90 | PTPN7 (1.00) | PTPN7DUSP3PTPN12PTPN22DUSP6 | |
| SCHEMBL4669327 | 0.86 | MEN1 (0.69) | PTPN7DUSP3PTPN12PTPN22DUSP6 | |
| SCHEMBL4669325 | 0.86 | MEN1 (0.69) | PTPN7DUSP3PTPN12PTPN22DUSP6 | |
| SCHEMBL12267452 | 0.84 | PTPN7 (0.90) | PTPN7DUSP3PTPN12PTPN22DUSP6 | |
| SCHEMBL13855965 | 0.81 | ALDH1A1 (0.76) | PTPN7DUSP3PTPN12PTPN22DUSP6 | |
| SCHEMBL13855903 | 0.80 | DUSP3 (0.65) | PTPN7DUSP3PTPN12PTPN22DUSP6 | |
| SCHEMBL4670262 | 0.77 | ALDH1A1 (0.84) | PTPN7DUSP3PTPN22DUSP6MAPT | |
| SCHEMBL4670263 | 0.77 | ALDH1A1 (0.84) | PTPN7DUSP3PTPN22DUSP6MAPT | |
| SCHEMBL4669378 | 0.77 | ALDH1A1 (0.81) | PTPN7DUSP3PTPN12PTPN22DUSP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9091678-B2 | Method for identifying compounds useful for treating and/or preventing disease-associated bone loss | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2015-07-28 | — | — | US | disclosed |
| US-20110212974-A1 | METHOD FOR IDENTIFYING COMPOUNDS USEFUL FOR TREATING AND/OR PREVENTING DISEASE-ASSOCIATED BONE LOSS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) | 2011-09-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110212974-A1 | METHOD FOR IDENTIFYING COMPOUNDS USEFUL FOR TREATING AND/OR PREVENTING DISEASE-ASSOCIATED BONE LOSS | DOCK5, ARHGDIB, ARHGDIA | PTPN7 3264/4885DUSP3 611/4885PTPN12 3921/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.