Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | P4HB | P07237 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10092716 | 0.80 | GABRA1 (0.37) | GFERDRD2DRD4NOTUM | |
| SCHEMBL22311516 | 0.80 | GFER (0.33) | GFERPARP1PARP10DRD2DRD4 | |
| SCHEMBL30768024 | 0.77 | NOTUM (0.36) | PARP1PARP10DRD2DRD4NOTUM | |
| SCHEMBL1405509 | 0.77 | NOTUM (0.36) | PARP1PARP10DRD2DRD4NOTUM | |
| SCHEMBL23384792 | 0.76 | UHRF1 (0.34) | PARP1PARP10NOTUM | |
| SCHEMBL1405476 | 0.72 | NOTUM (0.50) | PARP1PARP10DRD2DRD4NOTUM | |
| SCHEMBL24713940 | 0.72 | NOTUM (0.33) | PARP1PARP10NOTUM | |
| SCHEMBL26431777 | 0.72 | ALDH1A1 (0.34) | PARP1PARP10NOTUM | |
| SCHEMBL27445745 | 0.71 | P4HB (0.39) | GFERP4HBPARP1PARP10DRD2 | |
| SCHEMBL21029685 | 0.70 | NOTUM (0.32) | PARP10NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021219091-A2 | QUINOXALINONE DERIVATIVE AS IRREVERSIBLE INHIBITOR OF KRAS G12C MUTANT PROTEIN | 北京泰德制药股份有限公司 (CN) | 2021-11-04 | — | — | WO | disclosed |