Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 3/20 | 0.51 |
| ▸ | HTR1B | P28222 | 3/20 | 0.51 |
| ▸ | QDPR | P09417 | 2/20 | 0.40 |
| ▸ | WEE1 | P30291 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | HTR1F | P30939 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26040667 | 0.86 | HTR1D (0.52) | HTR1DHTR1BQDPRCYP1A2CYP3A4 | |
| SCHEMBL29310322 | 0.84 | HTR1D (0.50) | HTR1DHTR1BQDPRCYP1A2CYP3A4 | |
| SCHEMBL22542018 | 0.83 | QDPR (0.41) | HTR1DHTR1BQDPRWEE1CYP1A2 | |
| SCHEMBL13476645 | 0.82 | NUDT1 (0.41) | HTR1DHTR1BMAPTACHEKDM4E | |
| SCHEMBL26640506 | 0.81 | HTR1D (0.48) | HTR1DHTR1BQDPRCYP1A2CYP3A4 | |
| SCHEMBL16825003 | 0.81 | RBP4 (0.35) | HTR1DHTR1BCYP2C9ACHE | |
| SCHEMBL24478536 | 0.81 | HTR2A (0.41) | HTR1DHTR1BQDPRWEE1CYP1A2 | |
| SCHEMBL24451796 | 0.79 | HTR2A (0.40) | HTR1DHTR1BQDPRWEE1CYP1A2 | |
| SCHEMBL5140978 | 0.78 | DRD2 (0.44) | KDM4EDRD2 | |
| SCHEMBL522141 | 0.78 | HTR1D (0.56) | HTR1DHTR1BQDPRCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230192701-A1 | BICYCLIC KINASE INHIBITORS AND USES THEREOF | IOMX THERAPEUTICS AG (DE) | 2023-06-22 | — | — | US | disclosed |
| WO-2021219731-A2 | BICYCLIC KINASE INHIBITORS AND USES THEREOF | IOMX THERAPEUTICS AG (DE) | 2021-11-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230192701-A1 | BICYCLIC KINASE INHIBITORS AND USES THEREOF | MITF, PRKDC, PRKACA | HTR1D 2745/4885HTR1B 3194/4885QDPR 3788/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.