Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.64 |
| ▸ | MEN1 | O00255 | 6/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 3/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | MMP13 | P45452 | 2/20 | 0.56 |
| ▸ | APP | P05067 | 1/20 | 0.56 |
| ▸ | MMP2 | P08253 | 1/20 | 0.56 |
| ▸ | MMP9 | P14780 | 1/20 | 0.56 |
| ▸ | MMP8 | P22894 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2118960 | 0.77 | MMP13 (0.58) | MAPTMEN1KMT2ANPSR1HTT | |
| SCHEMBL2118962 | 0.76 | KAT8 (0.59) | MAPTMEN1KMT2ANPSR1HTT | |
| SCHEMBL1228438 | 0.76 | KAT8 (0.59) | MAPTMEN1KMT2ANPSR1HTT | |
| SCHEMBL3355186 | 0.75 | MAPT (0.70) | MAPTMEN1KMT2ANPSR1HTT | |
| SCHEMBL27876738 | 0.74 | ALDH1A1 (0.58) | MAPTMEN1KMT2ANPSR1HTT | |
| 2-Mercaptobenzothiazole SCHEMBL28269969 | 0.73 | MMP13 (0.66) | MAPTMEN1KMT2ANPSR1HTT | |
| SCHEMBL687502 | 0.73 | MAPT (0.68) | MAPTMEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL687503 | 0.73 | MAPT (0.68) | MAPTMEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL10665075 | 0.72 | MMP13 (0.57) | MAPTMEN1KMT2ANPSR1HTT | |
| SCHEMBL686788 | 0.72 | THRB (0.52) | MAPTMEN1KMT2ANPSR1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210338694-A1 | SOS1 ALLOSTERIC SITE TARGETING | UNIVERSITY OF CINCINNATI | 2021-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210338694-A1 | SOS1 ALLOSTERIC SITE TARGETING | SOS1, SOS2, SOST | MAPT 4141/4885MEN1 554/4885KMT2A 3592/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.