Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 13/20 | 0.44 |
| ▸ | ICAM1 | P05362 | 13/20 | 0.44 |
| ▸ | ITGAL | P20701 | 13/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23978731 | 0.94 | MAPT (0.51) | ITGB2ICAM1ITGALMAPTTDP1 | |
| SCHEMBL23978786 | 0.88 | ITGB2 (0.54) | ITGB2ICAM1ITGALITGA4 | |
| SCHEMBL23979136 | 0.87 | ITGA4 (0.38) | ITGB2ICAM1ITGALTDP1ITGA4 | |
| SCHEMBL30083840 | 0.84 | EPHX2 (0.43) | ITGB2ICAM1ITGALMAPTTDP1 | |
| SCHEMBL24803486 | 0.84 | EPHX2 (0.43) | ITGB2ICAM1ITGALMAPTTDP1 | |
| SCHEMBL24805463 | 0.84 | EPHX2 (0.43) | ITGB2ICAM1ITGALMAPTTDP1 | |
| SCHEMBL23979004 | 0.80 | MAPT (0.48) | ITGB2ICAM1ITGALMAPTTDP1 | |
| SCHEMBL30083856 | 0.80 | MAPT (0.48) | ITGB2ICAM1ITGALMAPTTDP1 | |
| SCHEMBL23978696 | 0.79 | TACR1 (0.46) | MAPTKMT2A | |
| SCHEMBL23979116 | 0.78 | ITGA4 (0.39) | ITGALMAPTTDP1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021222789-A1 | INHIBITORS OF ALPHA 2 BETA 1 INTEGRIN AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-11-04 | — | — | WO | disclosed |