Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 1/20 | 0.38 |
| ▸ | ITGB2 | P05107 | 4/20 | 0.37 |
| ▸ | ICAM1 | P05362 | 4/20 | 0.37 |
| ▸ | ITGAL | P20701 | 4/20 | 0.37 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.37 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.37 |
| ▸ | ACLY | P53396 | 1/20 | 0.37 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | F13A1 | P00488 | 1/20 | 0.36 |
| ▸ | TGM2 | P21980 | 1/20 | 0.36 |
| ▸ | TGM1 | P22735 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SPR | P35270 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23979116 | 0.88 | ITGA4 (0.39) | ITGA4ITGALITGB1ITGA5ACE | |
| SCHEMBL23978784 | 0.87 | ITGB2 (0.44) | ITGA4ITGB2ICAM1ITGALTDP1 | |
| SCHEMBL24803484 | 0.85 | EPHX2 (0.42) | ITGB2ICAM1ITGALTDP1 | |
| SCHEMBL30083845 | 0.85 | EPHX2 (0.42) | ITGB2ICAM1ITGALTDP1 | |
| SCHEMBL23978804 | 0.85 | EPHX2 (0.42) | ITGB2ICAM1ITGALTDP1 | |
| SCHEMBL24804256 | 0.85 | EPHX2 (0.42) | ITGB2ICAM1ITGALTDP1 | |
| SCHEMBL23978731 | 0.83 | MAPT (0.51) | ITGB2ICAM1ITGALTDP1 | |
| SCHEMBL23978696 | 0.77 | TACR1 (0.46) | POLB | |
| SCHEMBL23978763 | 0.76 | ITGB1 (0.46) | ITGB1ITGA5ACEPOLB | |
| SCHEMBL23978822 | 0.76 | ITGA4 (0.45) | ITGA4ITGB2ICAM1ITGALITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021222789-A1 | INHIBITORS OF ALPHA 2 BETA 1 INTEGRIN AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-11-04 | — | — | WO | disclosed |