Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAL | P20701 | 3/20 | 0.39 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.39 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 12/20 | 0.39 |
| ▸ | ITGA5 | P08648 | 6/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 8/20 | 0.39 |
| ▸ | ITGAV | P06756 | 2/20 | 0.36 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.36 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.35 |
| ▸ | ITGB8 | P26012 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23979049 | 0.91 | P2RX3 (0.36) | ITGALITGB2ICAM1ITGB1ITGA5 | |
| SCHEMBL30279393 | 0.81 | ALDH1A1 (0.42) | ITGALITGB2ICAM1ITGB1ITGA5 | |
| SCHEMBL26104284 | 0.81 | ALDH1A1 (0.42) | ITGALITGB2ICAM1ITGB1ITGA5 | |
| SCHEMBL23979045 | 0.81 | ALDH1A1 (0.42) | ITGALITGB2ICAM1ITGB1ITGA5 | |
| SCHEMBL23978619 | 0.81 | ALDH1A1 (0.42) | ITGALITGB2ICAM1ITGB1ITGA5 | |
| SCHEMBL30337539 | 0.78 | MEN1 (0.41) | PTGER3 | |
| SCHEMBL23979021 | 0.78 | MEN1 (0.41) | PTGER3 | |
| SCHEMBL23978790 | 0.77 | LMNA (0.41) | ITGALITGB2ICAM1ITGB1ITGA5 | |
| SCHEMBL21376654 | 0.76 | ITGB2 (0.59) | ITGALITGB2ICAM1ITGB1ITGA5 | |
| SCHEMBL23979022 | 0.74 | MAPT (0.41) | PTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021222789-A1 | INHIBITORS OF ALPHA 2 BETA 1 INTEGRIN AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-11-04 | — | — | WO | disclosed |