Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.35 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.34 |
| ▸ | FADS1 | O60427 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.33 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.33 |
| ▸ | ITGAL | P20701 | 2/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23978982 | 0.91 | ITGAL (0.39) | ITGB1ITGA5SYKPTGER3ITGB2 | |
| SCHEMBL23979060 | 0.81 | USP2 (0.43) | TAS1R3TAS1R1 | |
| SCHEMBL26493531 | 0.81 | USP2 (0.43) | TAS1R3TAS1R1 | |
| SCHEMBL24803327 | 0.81 | USP2 (0.43) | TAS1R3TAS1R1 | |
| SCHEMBL23979022 | 0.77 | MAPT (0.41) | P2RX3CA2PTGER3FADS1RAB9A | |
| SCHEMBL23978642 | 0.76 | LNPEP (0.39) | ITGB1ITGA5ITGB2ICAM1ITGAL | |
| SCHEMBL23978639 | 0.76 | KCNQ2 (0.42) | ITGB1ITGA5 | |
| SCHEMBL23978646 | 0.76 | INSR (0.36) | ITGB1ITGA5TAS1R3TAS1R1 | |
| SCHEMBL23979021 | 0.75 | MEN1 (0.41) | P2RX3CA2PTGER3FADS1SMN1; SMN2 | |
| SCHEMBL30337539 | 0.75 | MEN1 (0.41) | P2RX3CA2PTGER3FADS1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021222789-A1 | INHIBITORS OF ALPHA 2 BETA 1 INTEGRIN AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-11-04 | — | — | WO | disclosed |