Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | TP53 | P04637 | 1/20 | 0.69 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.67 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | NT5E | P21589 | 1/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10625750 | 1.00 | LMNA (0.69) | LMNATP53ADORA2AADORA2BHPGD | |
| SCHEMBL23982067 | 1.00 | LMNA (0.69) | LMNATP53ADORA2AADORA2BHPGD | |
| SCHEMBL20419320 | 0.88 | ADORA3 (0.69) | LMNATP53ADORA2AADORA2BHPGD | |
| SCHEMBL17268353 | 0.88 | ADORA3 (0.69) | LMNATP53ADORA2AADORA2BHPGD | |
| SCHEMBL20419161 | 0.88 | ADORA3 (0.69) | LMNATP53ADORA2AADORA2BHPGD | |
| SCHEMBL22757333 | 0.88 | LMNA (0.66) | LMNATP53ADORA2AADORA2BHPGD | |
| SCHEMBL23982228 | 0.81 | LMNA (1.00) | LMNATP53ADORA2AADORA2BHPGD | |
| SCHEMBL638999 | 0.81 | LMNA (1.00) | LMNATP53ADORA2AADORA2BHPGD | |
| SCHEMBL10607959 | 0.81 | LMNA (1.00) | LMNATP53ADORA2AADORA2BHPGD | |
| SCHEMBL29601320 | 0.81 | LMNA (1.00) | LMNATP53ADORA2AADORA2BHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210338706-A1 | ADENOSINE ANALOG AND ITS USE IN REGULATING THE CIRCADIAN CLOCK | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2021-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210338706-A1 | ADENOSINE ANALOG AND ITS USE IN REGULATING THE CIRCADIAN CLOCK | PER2, CRY1, ADORA2A | LMNA 2993/4885TP53 4641/4885ADORA2A 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.