Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 9/20 | 0.50 |
| ▸ | RXRB | P28702 | 9/20 | 0.50 |
| ▸ | RXRG | P48443 | 6/20 | 0.50 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.47 |
| ▸ | BAD | Q92934 | 1/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17596594 | 0.83 | RXRA (0.50) | RXRARXRBRXRGBCL2L1BAD | |
| SCHEMBL5833456 | 0.81 | RXRA (0.49) | RXRARXRBRXRGBCL2L1BAD | |
| SCHEMBL29062395 | 0.80 | RXRA (0.48) | RXRARXRBRXRGBCL2L1BAD | |
| SCHEMBL11221730 | 0.79 | RXRB (0.50) | RXRARXRBRXRGBCL2L1BAD | |
| SCHEMBL7206062 | 0.79 | RXRA (0.50) | RXRARXRBRXRGBCL2L1BAD | |
| SCHEMBL1872704 | 0.79 | LMNA (0.51) | RXRARXRBRXRGBCL2L1BAD | |
| SCHEMBL9791358 | 0.76 | RXRA (0.45) | RXRARXRBRXRGBCL2L1BAD | |
| SCHEMBL27705529 | 0.76 | RXRA (0.47) | RXRARXRBRXRGBCL2L1BAD | |
| SCHEMBL6630115 | 0.75 | GAA (0.49) | RXRARXRBRXRGLMNASMN1; SMN2 | |
| SCHEMBL31312989 | 0.75 | BCL2L1 (0.54) | RXRARXRBRXRGBCL2L1BAD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364312-A2 | PREPARATION OF CRYSTALLINE PALONOSETRON HYDROCHLORIDE | Dr. Reddy's Laboratories, Ltd. (IN) | 2011-09-14 | — | — | EP | disclosed |
| US-20110213150-A1 | PREPARATION OF CRYSTALLINE PALONOSETRON HYDROCHLORIDE | DR. REDDY'S LABORATORIES LTD. (IN) | 2011-09-01 | — | — | US | disclosed |
| WO-2010056656-A2 | PREPARATION OF CRYSTALLINE PALONOSETRON HYDROCHLORIDE | DR. REDDY'S LABORATORIES LTD. (IN) | 2010-05-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110213150-A1 | PREPARATION OF CRYSTALLINE PALONOSETRON HYDROCHLORIDE | HTR3A, HTR5A, HTR3C | RXRA 3729/4885RXRB 3683/4885RXRG 3414/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.