SCHEMBL2398565

SCHEMBL2398565

CSc1ccc(CC(C)=O)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.48
SLC6A4 P31645 7/20 0.45
ACACB O00763 1/20 0.44
PLK1 P53350 1/20 0.44
MAOA P21397 1/20 0.44
SLC6A2 P23975 1/20 0.44
SLC6A3 Q01959 1/20 0.44
KDM4E B2RXH2 2/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
ATM Q13315 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
EPHX2 P34913 1/20 0.42
NR1H4 Q96RI1 1/20 0.42
MMP12 P39900 1/20 0.42
MMP13 P45452 1/20 0.42
ALDH1A1 P00352 2/20 0.42
LMNA P02545 1/20 0.42
TSHR P16473 1/20 0.42
HSD17B10 Q99714 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9260939 0.89 POLB (0.53) POLBSLC6A4KDM4EMEN1KMT2A
SCHEMBL15693005 0.83 POLB (0.46) POLBACACBKDM4EKMT2AALDH1A1
SCHEMBL8403545 0.83 POLB (0.61) POLBKMT2AALDH1A1LMNATSHR
SCHEMBL46640 0.83 CA2 (0.56) POLBSLC6A4KDM4EMEN1KMT2A
SCHEMBL9377377 0.81 POLB (0.47) POLBKDM4EMEN1KMT2AATM
SCHEMBL3490695 0.81 CA2 (0.57) SLC6A4MAOASLC6A2SLC6A3
SCHEMBL2407621 0.81 SMN1; SMN2 (0.46) SLC6A4PLK1MAOASLC6A2SLC6A3
SCHEMBL11004878 0.79 SLC6A4 (0.47) POLBSLC6A4MAOAMEN1KMT2A
SCHEMBL7953221 0.79 ALDH1A1 (0.59) SLC6A4ACACBPLK1MAOASLC6A2
SCHEMBL6167644 0.79 SLC6A4 (0.46) SLC6A4PLK1MAOASLC6A2SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108623726-A 3 D-printing cashew nut phenol resin and preparation method thereof 闽江学院 2018-10-09 CN claimed
CN-108538595-A Capacitor and preparation method thereof based on heat-resisting ionic gel electrolyte 中南大学 2018-09-14 CN claimed
EP-4169925-A2 PROCESS TO MAKE N-SUBSTITUTED TETRAHYDROTHIENOPYRIDINE DERIVATIVES Novartis AG (CH) 2023-04-26 EP disclosed
EP-3464317-B1 AMINOSTEROID DERIVATIVES AND PROCESS FOR PRODUCING SAME UNIV LAVAL (CA) 2023-04-26 EP disclosed
US-11174282-B2 Aminosteroid derivatives and process for producing same UNIVERSITé LAVAL (CA) 2021-11-16 US disclosed
CN-112716821-A Low-odor UV crystal liquid and curing method thereof 金华市科维思日化有限公司 2021-04-30 CN disclosed
CN-213021053-U Be used for producing condenser to methylthio propiophenone 无极县腾益利化工有限公司 2021-04-20 CN disclosed
CN-106414570-B resin product 三菱化学株式会社 2019-09-10 CN disclosed
CN-109867760-A A kind of 3D printing cashew nut phenolic group photosensitive resin and preparation method thereof 泉州师范学院 2019-06-11 CN disclosed
CN-106458774-B Laminated film for forming concrete surface covering layer, building material made of concrete, and method for producing same 三菱化学株式会社 2019-06-04 CN disclosed
CN-108391380-A The preparation method of flexible circuit board 深圳市爱升精密电路科技有限公司 2018-08-10 CN disclosed
EP-0924194-A2 Processes for producing optically active 2-amino-1-phenylethanol derivatives DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1999-06-23 EP disclosed
WO-1999018093-A1 NOVEL 3,4-DIARYLTHIAZOLIN-2-ONE OR -2-THIONE DERIVATIVES, PREPARATION METHODS AND USES IN THERAPY LABORATOIRES UPSA (FR) 1999-04-15 WO disclosed
US-5859257-A ANTIINFLAMMATORY, ANTIARTHRITIC AGENTS G. D. SEARLE & CO. (US) 1999-01-12 US disclosed
US-5811293-A CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1998-09-22 US disclosed
EP-0809636-A1 SUBSTITUTED ISOXAZOLES FOR THE TREATMENT OF INFLAMMATION G.D. SEARLE & CO. (US) 1997-12-03 EP disclosed
WO-1996025405-A1 SUBSTITUTED ISOXAZOLES FOR THE TREATMENT OF INFLAMMATION G.D. SEARLE & CO. (US) 1996-08-22 WO disclosed
EP-0654534-A2 Processes for producing optically active 2-amino-1-phenylethanol derivatives DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1995-05-24 EP disclosed
US-4517192-A 6-Alkyl-5-[4-(alkylsulfinyl or alkylsulfonyl)phenyl]-2(1H)-pyridinones and their use as cardiatonics STERLING DRUG INC. (US) 1985-05-14 US disclosed
EP-0089154-A2 Ethanolamine derivatives, their preparation and use in pharmaceutical compositions BEECHAM GROUP PLC (GB) 1983-09-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11174282-B2 Aminosteroid derivatives and process for producing same HSD17B11, HSD17B7, CYP19A1 POLB 2608/4885SLC6A4 3053/4885ACACB 545/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.