SCHEMBL2398643

SCHEMBL2398643

O=C(O)CC(CC1CCCC1)C(=O)N(c1nc(-c2ccccc2-c2cnc(N3CCCC3=O)c(Cl)c2)cs1)C1CC1

nearest known ligand 0.64

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
FFAR2 O15552 11/20 0.64
CNR2 P34972 1/20 0.33
UCHL1 P09936 1/20 0.32
USP30 Q70CQ3 1/20 0.32
MALT1 Q9UDY8 1/20 0.31
SLC12A5 Q9H2X9 2/20 0.31
MPL P40238 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1916595 1.00 FFAR2 (0.64) FFAR2CNR2UCHL1USP30MALT1
SCHEMBL1915971 0.92 FFAR2 (0.64) FFAR2
SCHEMBL1915968 0.92 FFAR2 (0.64) FFAR2
SCHEMBL1916204 0.89 FFAR2 (0.75) FFAR2CNR2SLC12A5
SCHEMBL1917149 0.89 FFAR2 (0.75) FFAR2CNR2SLC12A5
SCHEMBL16498009 0.88 FFAR2 (0.73) FFAR2CNR2UCHL1SLC12A5
SCHEMBL16498011 0.88 FFAR2 (0.73) FFAR2CNR2UCHL1SLC12A5
SCHEMBL1915979 0.87 FFAR2 (0.74) FFAR2CNR2SLC12A5
SCHEMBL1915975 0.87 FFAR2 (0.74) FFAR2CNR2SLC12A5
SCHEMBL1916133 0.86 FFAR2 (0.63) FFAR2CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110230477-A1 COMPOUNDS, PHARMACEUTICAL COMPOSITION AND METHODS FOR USE IN TREATING METABOLIC DISORDERS EUROSCREEN S.A. (BE) 2011-09-22 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110230477-A1 COMPOUNDS, PHARMACEUTICAL COMPOSITION AND METHODS FOR USE IN TREATING METABOLIC DISORDERS CPT1A, LIPC, PC FFAR2 295/4885CNR2 822/4885UCHL1 3346/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.