Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA4 | P48058 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23987254 | 0.85 | TSHR (0.42) | GRIA4TSHRSMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL25039583 | 0.81 | GRIA4 (0.41) | GRIA4TSHRSMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL4164946 | 0.77 | TDP1 (0.46) | TSHRSMN1; SMN2ALDH1A1TP53HSP90AA1 | |
| SCHEMBL23987222 | 0.73 | KIF11 (0.42) | TSHRSMN1; SMN2ALDH1A1CYP3A4HDAC3 | |
| SCHEMBL9501204 | 0.72 | TSHR (0.46) | TSHRSMN1; SMN2ALDH1A1CYP3A4HDAC3 | |
| SCHEMBL11347493 | 0.72 | TSHR (0.72) | GRIA4TSHRSMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL8359955 | 0.70 | TDP1 (0.52) | TSHRSMN1; SMN2ALDH1A1TP53HSP90AA1 | |
| SCHEMBL13382108 | 0.69 | KIF11 (0.46) | GRIA4TSHRSMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL25039432 | 0.69 | LMNA (0.39) | SMN1; SMN2HDAC3HDAC8HDAC6MAPT | |
| SCHEMBL24636607 | 0.69 | TSHR (0.45) | GRIA4TSHRSMN1; SMN2ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210338610-A1 | AMINO-ARYL-BENZAMIDE COMPOUNDS AND METHODS OF USE THEREOF | HEPANOVA, INC. | 2021-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210338610-A1 | AMINO-ARYL-BENZAMIDE COMPOUNDS AND METHODS OF USE THEREOF | AADAC, GOT2, ABAT | GRIA4 3263/4885TSHR 1861/4885SMN1; SMN2 3705/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.