SCHEMBL23987343

SCHEMBL23987343

CO/C=C(/C(=O)OC)c1csc2ccc(-c3ccccc3)cc12

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR4A2 P43354 3/20 0.40
MEN1 O00255 3/20 0.37
KMT2A Q03164 3/20 0.37
POLB P06746 3/20 0.37
BCL2L1 Q07817 1/20 0.36
STK17B O94768 1/20 0.35
HDAC3 O15379 1/20 0.35
HDAC4 P56524 1/20 0.35
HDAC1 Q13547 1/20 0.35
HDAC7 Q8WUI4 1/20 0.35
HDAC2 Q92769 1/20 0.35
HDAC10 Q969S8 1/20 0.35
HDAC11 Q96DB2 1/20 0.35
HDAC8 Q9BY41 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35
HDAC9 Q9UKV0 1/20 0.35
HDAC5 Q9UQL6 1/20 0.35
KDM4E B2RXH2 2/20 0.35
MAPT P10636 2/20 0.35
CYP1A2 P05177 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9218225 0.84 ALDH1A1 (0.37) MEN1KMT2APOLBHDAC3HDAC4
SCHEMBL9220655 0.83 MAPT (0.41) NR4A2MEN1KMT2APOLBMAPT
SCHEMBL9220714 0.81 MTNR1A (0.47) NR4A2MEN1KMT2AKDM4EMAPT
SCHEMBL9211264 0.81 ALDH1A1 (0.34) MEN1KMT2APOLBHDAC3HDAC4
SCHEMBL9215653 0.80 FFAR1 (0.47) MEN1KMT2A
SCHEMBL9209687 0.79 TBXAS1 (0.36) MEN1KMT2AKDM4EMAPTCYP1A2
SCHEMBL10552187 0.78 NR4A2 (0.41) NR4A2HPGDALDH1A1DHODH
SCHEMBL10552181 0.78 NR4A2 (0.41) NR4A2HPGDALDH1A1DHODH
SCHEMBL9219061 0.78 MAPT (0.43) KDM4EMAPTCYP1A2HPGDALDH1A1
SCHEMBL23987220 0.78 MEN1 (0.39) MEN1KMT2AHDAC2KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021219775-A1 MICROBIOCIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2021-11-04 WO disclosed