Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | METAP1 | P53582 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23975886 | 0.92 | KDM4E (0.48) | KDM4EALDH1A1HPGDRAB9AALPL | |
| SCHEMBL23976260 | 0.91 | KDM4E (0.46) | KDM4EALDH1A1HPGDRAB9AALPL | |
| SCHEMBL23975855 | 0.88 | ALDH1A1 (0.44) | KDM4EALDH1A1HPGDRAB9AALPL | |
| SCHEMBL23975881 | 0.86 | LMNA (0.45) | KDM4EALDH1A1HPGDRAB9AALPL | |
| SCHEMBL23976261 | 0.85 | METAP2 (0.44) | KDM4EALDH1A1HPGDRAB9AALPL | |
| SCHEMBL25934447 | 0.83 | KDM4E (0.40) | KDM4EALDH1A1HPGDRAB9AALPL | |
| SCHEMBL23976561 | 0.82 | NOTUM (0.50) | KDM4EALDH1A1RAB9AKMT2AMEN1 | |
| SCHEMBL23975837 | 0.82 | KDM4E (0.45) | KDM4EALDH1A1HPGDRAB9AALPL | |
| SCHEMBL23975816 | 0.82 | L3MBTL1 (0.49) | HPGDRAB9AKMT2AADORA2AADORA3 | |
| SCHEMBL25312800 | 0.81 | NCOA3 (0.48) | KMT2ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021222359-A1 | THIENO PYRIMIDINES AS FERROPORTIN INHIBITORS | GLOBAL BLOOD THERAPEUTICS, INC. (US) | 2021-11-04 | — | — | WO | disclosed |