Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MASP2 | O00187 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.35 |
| ▸ | ESRRG | P62508 | 1/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3144723 | 0.84 | NPC1 (0.44) | CYP19A1LMNACYP1A2CYP3A4MAOA | |
| SCHEMBL2399414 | 0.78 | MAOA (0.47) | MAOA | |
| SCHEMBL11698205 | 0.76 | CYP19A1 (0.54) | CYP19A1LMNACYP1A2CYP3A4MAOA | |
| SCHEMBL14041429 | 0.75 | LMNA (0.46) | CYP19A1LMNACYP1A2CYP3A4MAOA | |
| SCHEMBL508101 | 0.75 | GSK3B (0.42) | CYP19A1LMNAEPHX2 | |
| SCHEMBL15868678 | 0.75 | MAOA (0.34) | CYP19A1MAOAMASP2PLAUTHPO | |
| SCHEMBL23792863 | 0.74 | HDAC1 (0.47) | MAOA | |
| SCHEMBL23793503 | 0.73 | ALDH1A1 (0.37) | THRB | |
| SCHEMBL14330440 | 0.72 | CYP19A1 (0.45) | CYP19A1LMNACYP1A2CYP3A4MAOA | |
| SCHEMBL10856840 | 0.71 | PHLPP2 (0.43) | CYP19A1CYP3A4MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021178907-A1 | STAT INHIBITORY COMPOUNDS AND COMPOSITIONS | JANPIX, LTD. (US) | 2021-09-10 | — | — | WO | disclosed |